PROTEIN DETECTION
In the field of proteomics, protein microarrays and novel detection platforms are gaining popularity because of their potential in high throughput screening (HTS) and much improved sensitivities. Raman labels can be used in protein arrays as novel tags for systems that require very robust or high multiplexing properties. The probes are versatile and can easily be functionalized with different chemical groups such as NH2, COOH, SH, or molecules such as maleimide, biotin, poly(ethylene) glycol (PEG) which makes them ready for bioconjugation. Here, Raman label-PEG-Biot are captured by an array of patterned streptavidin on the surface demonstrating the specificity of the Raman label.